Conference Paper2025

Learning From Both Eyes: A Bilateral Ensemble Approach for Retinal Disease Classification

Sadia Alam Kotha, Abdullah Al Alam Shanto, Mumtahina Esha, Siam Tahsin Bhuiyan, Halima Khatun, Rashedur Rahman, Ashraful Islam, Saadia Binte Alam

2025 IEEE International Women in Engineering (WIE) Conference on Electrical and Computer Engineering (WIECON-ECE)

IEEE, pp. 480-485

  • Good Health and Well-being — Relevance: 95%

Abstract

Automated detection of retinal diseases from retinal color fundus images is crucial for early diagnosis and effective intervention. While deep learning approaches have achieved high accuracy, most existing methods analyze each eye independently and inconsistently apply preprocessing, limiting their ability to capture inter-eye asymmetries and subtle pathological features. In this study, we propose a bilateral ensemble framework for multi-class retinal disease classification using ConvNeXt-XLarge as the backbone. Fundus images were preprocessed with color normalization, a color correction technique to enhance feature consistency. Experiments were conducted on the ODIR-5K dataset, focusing on five clinically relevant categories: Normal, Diabetic Retinopathy, Cataract, Age-Related Macular Degeneration, and Myopia. We evaluated both single-eye and bilateral ensemble settings, with and without color correction, using Accuracy, Precision, Recall, F1 Score, Specificity. The bilateral ensemble with color-corrected images achieved the highest overall accuracy of 74.5 %, demonstrating that bilateral feature fusion and systematic preprocessing improve the model's ability to capture inter-eye asymmetries and subtle retinal patterns. These results underscore the potential of ensemble-based approaches to provide more reliable and clinically meaningful automated retinal disease detection.

Keywords

  • age-related macular degeneration
  • myopia
  • retinal disease classification
  • cataract
  • diabetic retinopathy
  • color fundus images
  • color correction

CCDS Authors

Siam Tahsin Bhuiyan
Siam Tahsin Bhuiyan

Siam Tahsin Bhuiyan

  • Intern, CCDS

Bachelors

Independent University, Bangladesh

Published at

Scientific Reports

Halima Khatun
Halima Khatun

Halima Khatun

  • Research Assistant, CCDS

Bachelors

Independent University, Bangladesh

Published at

Scientific Reports

Md. Rashedur Rahman, D. Eng.
Md. Rashedur Rahman, D. Eng.

Md. Rashedur Rahman, D. Eng.

  • Co-Director, MIRA & NEST Wings

Assistant Professor

Department of Computer Science and Engineering

Independent University, Bangladesh

Published at

CHI, HCII, Scientific Reports, Cognitive Computation, Neural Computing and Applications

Ashraful Islam, PhD
Ashraful Islam

Ashraful Islam, PhD

  • Center Director, CCDS
  • Director, HCI Wing

Assistant Professor

Department of Computer Science and Engineering

Independent University, Bangladesh (IUB)

Published at

CHI, UIST, UbiComp, IJCNN, ICIP, HCII, ICDMW, BLP, IEEE Internet of Things Journal, JMIR, JMIR Human Factors, JMIR Formative Research, IEEE Access, Smart Agricultural Technology, Diabetes Research and Clinical Practice, PLOS ONE

Research Interests

Human-Computer Interaction, AI for Social Good, AI for Public Health, AI for Impact

Saadia Binte Alam, PhD
Saadia Binte Alam, PhD

Saadia Binte Alam, PhD

  • Director, MIRA & WiSE Wings

Associate Professor

Department of Computer Science and Engineering

Independent University, Bangladesh

Published at

HCII, Scientific Reports, Cognitive Computation, Neural Computing and Applications

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