Predicting Association Between Entities in Heterogeneous Biological Networks

Heterogeneity is inherent in biological networks which consist of different entities as nodes (i.e., genes, diseases, drugs, function) and represent the relationships between these entities as edges. Predicting potential associations between biological entities currently has been an important problem in biomedical research. In general, a deep learning model uses the contextual information and structures of the heterogeneous networks to identify the associations. This project will utilize powerful tools, e.g., GNN & MRF, to develop a more accurate, explainable model for link predictions in heterogeneous networks. Dr. Azad Abul Kalam will collaborate with us on this project.